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Related Concept Videos

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Biomarkers.

Pamela Lopes da Cunha1,2, Agustina Selser2, Lucia Amoruso2,3

  • 1Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 25, 2025
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Summary
This summary is machine-generated.

This study created a Spanish social concept database to aid behavioral-variant frontotemporal dementia (bvFTD) research in Latino populations. The database distinguishes social and non-social words, supporting differential diagnosis and neurological studies.

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Area of Science:

  • Neuroscience
  • Psycholinguistics
  • Cognitive Psychology

Background:

  • Behavioral-variant frontotemporal dementia (bvFTD) is linked to deficits in processing social concepts.
  • Normative datasets for social concepts are lacking in under-represented languages, hindering research.
  • A new psycholinguistic database of social and non-social concepts for Spanish speakers is needed.

Purpose of the Study:

  • To create a normative psycholinguistic database of social and non-social concepts for Spanish-speaking Latinos.
  • To facilitate research on social cognition in bvFTD within this under-served population.
  • To support differential diagnosis and identify neural alterations associated with bvFTD.

Main Methods:

  • Healthy adult Spanish speakers rated 600 Spanish words for social relevance using an online Likert scale.
  • Stimuli included high (e.g., "friendship") and low (e.g., "button") sociality words, selected based on prior methodology.
  • Participants were recruited via online platforms and social media.

Main Results:

  • Social words averaged a high socialness rating (M=5.997, SD=0.873), while non-social words received low ratings (M=1.75, SD=0.909).
  • Response consistency was higher at the extremes of the sociality scale.
  • The results demonstrate strong face validity and a clear distinction between social and non-social word categories.

Conclusions:

  • The developed Spanish social concept database is a valuable linguistic tool for studying social cognition in bvFTD.
  • This resource will enhance clinical investigation and diagnoses for Spanish-speaking populations, promoting research equity.
  • The database fosters translational research and incorporates a crucial Latin American perspective in behavioral neurology.