Prostatic Abscess Due to Dual Infection With Mycobacterium tuberculosis and Stenotrophomonas maltophilia

Prostatic abscess as an isolated entity is an infrequent and extremely rare manifestation of genitourinary tuberculosis. We report a case of a middle-aged male with type 2 diabetes mellitus and hypertension who presented with persistent lower urinary tract symptoms and fever. Imaging revealed a multiloculated prostatic abscess. Pus culture grew Stenotrophomonas maltophilia, while a cartridge-based nucleic acid amplification test confirmed Mycobacterium tuberculosis. The patient was managed with appropriate antimicrobial therapy, antitubercular treatment, and supportive care, leading to complete resolution of the abscess. This case underscores the diagnostic challenge posed by dual-pathogen prostatic abscesses and emphasizes the need to consider a tuberculous etiology even in the absence of pulmonary involvement, especially in endemic regions.