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Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

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The cerebellar-related cognitive function is sensitive to aging: implications for early detection.

Qianying Ma^1,2,3, Min Pu⁴, Meijia Li⁵

¹Cognitive Science and Allied Health School, Beijing Language and Culture University, Beijing, China.

Frontiers in Aging Neuroscience

|December 25, 2025

Summary

Older adults show specific cerebellar cognitive impairments, distinct from general cognitive scores. This highlights the need for targeted screening tools in aging research to assess cerebellar function.

Keywords:

aging cerebellar cognitive affective syndrome (CCAS) scale cerebellum middle-aged adults older perceptual serial reaction time task (SRT task)

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Area of Science:

Neuroscience
Cognitive Psychology
Gerontology

Background:

The cerebellum's role in sensorimotor and cognitive functions is established.
The impact of aging on cerebellar cognitive functions in healthy individuals is not well understood.

Purpose of the Study:

To investigate age-related changes in cerebellar cognitive functions.
To examine the relationship between cerebellar function and cognitive abilities in aging adults.

Main Methods:

Cross-sectional study with three age groups: early-middle (30-45), late-middle (46-57), and older adults (60-78).
Utilized the Cerebellar Cognitive Affective Syndrome (CCAS) scale and a perceptual serial reaction time (SRT) task.
All participants screened as cognitively healthy using the Mini-Mental State Examination (MMSE).

Main Results:

Older adults exhibited significant CCAS impairments (fluency, switching, memory, visuospatial skills) despite normal MMSE scores.
Older adults showed slower reaction times in the SRT task, indicating sensorimotor integration decline.
No age differences were found in learning new procedural knowledge; poorer CCAS scores correlated with slower SRT performance.

Conclusions:

A dissociation exists between general cognitive screening (MMSE) and specific cerebellar cognitive deficits in aging.
Cerebellar function is crucial for both sensorimotor and cognitive domains.
Screening tools sensitive to cerebellar function are vital for aging research.