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Related Experiment Video

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Study on the intervention effect of mindfulness-based stress reduction on postoperative cognitive dysfunction and

Xiaona Ji1, Haiyan Ding2, Yingtao Meng3

  • 1Ward One of Pulmonary Surgery, Cancer Hospital Affiliated to Shandong First Medical University, Jinan, China.

Frontiers in Neurology
|December 25, 2025
PubMed
Summary
This summary is machine-generated.

Mindfulness-Based Stress Reduction (MBSR) significantly improves cognitive function and psychological resilience in lung cancer patients post-surgery. This intervention also effectively reduces cancer-related fatigue and sleep disturbances, enhancing overall recovery and quality of life.

Keywords:
intervention effectlung cancermindfulness-based stress reductionpostoperative cognitive dysfunctionpsychological resilience

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Area of Science:

  • Oncology
  • Psychology
  • Mind-Body Medicine

Background:

  • Postoperative cognitive dysfunction and psychological distress significantly impair lung cancer patients' quality of life and recovery.
  • Mindfulness-Based Stress Reduction (MBSR) is an emerging psychological intervention gaining recognition in medical applications.

Purpose of the Study:

  • To evaluate the effectiveness of MBSR in improving postoperative cognitive function and psychological resilience among lung cancer patients.

Main Methods:

  • 86 lung cancer surgery patients were randomized into a control group (conventional care) and a research group (MBSR).
  • The intervention lasted 8 weeks, with outcomes assessed using standardized tools like MoCA, CD-RISC, GSES, PFS, and PSQI.
  • Statistical significance was determined by a p-value < 0.05.

Main Results:

  • MBSR significantly improved Montreal Cognitive Assessment (MoCA) scores (p < 0.001) and Connor-Davidson Resilience Scale (CD-RISC) scores (p = 0.012).
  • General Self-Efficacy Scale (GSES) scores were significantly higher in the MBSR group (p < 0.001).
  • MBSR significantly reduced Piper Fatigue Scale (PFS) scores (p < 0.05 for all subscales) and Pittsburgh Sleep Quality Index (PSQI) scores (p < 0.001).

Conclusions:

  • MBSR is an effective intervention for improving cognitive function and psychological resilience in lung cancer patients after surgery.
  • MBSR helps alleviate cancer-induced fatigue and sleep disorders, contributing to better patient outcomes and recovery.