[Cameron lesions and iron-deficiency anemia in patients with hiatal hernia]

To analyze the effectiveness of original laparoscopic fundoplication in correction of iron-deficiency anemia (IDA) following chronic blood loss from erosive and ulcerative lesions of esophageal and gastric mucosa in patients diagnosed with hiatal hernia (HH).

A prospective study included 42 patients with verified HH and concomitant IDA who underwent original laparoscopic fundoplication between 2023 and 2024. All patients underwent a comprehensive diagnostic algorithm including extended laboratory testing with assessment of red blood cell parameters and iron metabolism. Treatment efficacy was evaluated after 6 and 12 months through analysis of clinical and laboratory parameters.

Complete regression of gastroesophageal reflux disease was achieved in 39 patients (92.8%). Six-month laboratory monitoring demonstrated normalization of hemoglobin and serum iron levels in 35 out of 37 patients (94.5%). Normal hematological parameters were maintained after 12 months despite the absence of additional iron therapy during the second six-month period. This indicated stable clinical effect of surgical treatment and elimination of primary pathogenetic factor of anemia.

These data confirm high efficacy of surgical HH correction in treating refractory IDA associated with Cameron lesions and emphasize the need for timely detection of this pathology to optimize treatment strategy.