Related Experiment Video
Updated: Jan 7, 2026
Transauricular Vagus Nerve Stimulation and Electroencephalographic Assessment in Disorders of Consciousness
Published on: July 11, 2025
[Development of a Multimodal Auricular Vagus Nerve Stimulator with EEG Monitoring Capability]
Xiaohua Yu1,2, Guojing Wang1,2, Shijing Wu1,2
1Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100853.
Objective:
To address the limitations of existing auricular vagus nerve stimulators, which have a single stimulation mode and are open-loop, a new type of auricular vagus nerve stimulator system was developed.
Methods:
Based on the programmable general-purpose stimulator chip ENS001 and the integrated analog front-end chip ADS1299, an auricular vagus nerve stimulator capable of multi-channel EEG signal acquisition, multiple stimulation waveforms, and multiple stimulation modes was designed and developed.
Results:
The auricular vagus nerve stimulator, upon receiving parameter configuration instructions from the host computer, can generate four-channel output stimulation pulses with three types of waveforms and four modes (with an amplitude resolution of 0.1 mA, a frequency resolution of 1 Hz, and a pulse width resolution of 100 µs). The stimulator meets the requirements for the acquisition of human bioelectric signals and is capable of accurately acquiring human EEG signals.
Conclusion:
The auricular vagus nerve stimulator is simple in structure, low in manufacturing cost, portable, and has a wide range of adjustable stimulation parameters, showing great potential for application.
