Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuro-ocular amyloid characterization in Alzheimer's disease via cross-site PET-MRI and hierarchical cross-attention driven multimodal representation learning.

NeuroImage·2026
Same author

How do network structures of depressive symptoms differ between asian patients with bipolar depression and those with unipolar depression?

Asian journal of psychiatry·2026
Same author

Is Richard Baxter's Melancholia Still Relevant Today?: Comparative Network Structures of Depressive Symptoms in Asian Individuals With Guilt-Rich and Guilt-Free Depression.

Psychiatry investigation·2026
Same author

Relapsing Polychondritis Mimicking ANCA-Negative Granulomatosis with Polyangiitis: Diagnostic Value of <sup>18</sup>F-FDG PET/CT.

Diagnostics (Basel, Switzerland)·2026
Same author

Comparative Network Structures of Hikikomori (Social Withdrawal) Symptoms in Korean and Japanese Psychiatric Patients Prescribed Antidepressants: Findings From the Research on Asian Psychotropic Patterns for Antidepressants, Phase 3.

Journal of Korean medical science·2026
Same author

Combining EEG, event-related potentials, and MRI biomarkers for detection of mild cognitive impairment: A machine learning approach.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026

Related Experiment Video

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

Biomarkers.

Eun Hyun Seo1,2, Hyung-Jun Yoon3, Seung Gon Kim4

  • 1Premedical Science, College of Medicine, Chosun University, Gwangju, Korea, Republic of (South).

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 25, 2025
PubMed
Summary

The GARD visual memory test reliably detects early Alzheimer's disease (AD) cognitive changes. This tablet-based tool shows promise for identifying preclinical AD, aiding early diagnosis and intervention.

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Related Experiment Videos

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Area of Science:

  • Neuroscience
  • Gerontology
  • Medical Technology

Background:

  • Early detection of cognitive decline in Alzheimer's disease (AD) is critical.
  • Advancements in technology offer new avenues for neuropsychological assessments.
  • Developing sensitive tools for early AD detection is a key research priority.

Purpose of the Study:

  • To develop and validate a tablet-based visual memory paradigm for early AD detection.
  • To assess the reliability and validity of the GARD visual memory test.
  • To evaluate the test's potential in distinguishing cognitively normal from impaired individuals.

Main Methods:

  • The GARD visual memory test utilizes a delayed-matching-to-sample paradigm with Color, Shape, and Color-Shape conditions.
  • The test was developed using a cognitive neuroscience approach, parallel test sets, and user experience testing.
  • 131 cognitively normal (CN) and 71 cognitively impaired (CI) participants were assessed using the GARD test, neuropsychological batteries, and amyloid PET SUVR.

Main Results:

  • The GARD visual memory test demonstrated good reliability (ICC 0.4-0.8) and validity, correlating with established cognitive measures.
  • Scores were significantly influenced by age and education, but not gender.
  • The test effectively differentiated between CN and CI participants (p < 0.001) and showed correlations with amyloid PET SUVR.

Conclusions:

  • The GARD visual memory test is a reliable and valid tool for assessing visuospatial memory and detecting early cognitive changes in AD.
  • The test shows promise as a sensitive measure for identifying cognitive changes in preclinical AD.
  • Further validation, including biomarker and longitudinal studies, will enhance its clinical utility for early AD detection.