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The Medical Segmentation Decathlon without a Doctorate
Jessica Samir1, Karthik Ramadass2,3, Adam M Saunders3
1Dept. of Psychological Science and Neuroscience, Belmont University, Nashville, TN, USA.
Proceedings of Spie--The International Society for Optical Engineering
|December 26, 2025
Summary
A novice used AI-guided active learning (AL) for medical image segmentation, achieving comparable results to expert challenges. This demonstrates the potential of interactive AI frameworks for efficient segmentation tasks.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Machine Learning
Background:
- Accurate segmentation of anatomical structures is crucial for medical diagnosis and treatment planning.
- Active learning (AL) shows promise for developing AI segmentation algorithms interactively.
- Prospective studies on AL for medical image segmentation are limited.
Purpose of the Study:
- To assess if a novice could independently perform anatomical structure segmentation using AL and AI guidance.
- To evaluate the effectiveness of the MONAI Label framework for segmentation tasks.
- To compare segmentation performance against established benchmarks like the Medical Segmentation Decathlon (MSD).
Main Methods:
- A novice utilized the MONAI Label extension on 3D Slicer with AL techniques for segmentation.
- The study focused on pancreas and spleen segmentation challenges from the MSD.
- Radiopaedia and clinician-generated labels were used for novice education and AI model training.
Main Results:
- Segmentation yielded Dice scores of 0.209 for the pancreas (70 images) and 0.831 for the spleen (34 images).
- Spleen segmentation results fell within the MSD's reported range (0.83-0.97).
- Pancreas segmentation results were below the MSD's L1 region range (0.48-0.80).
Conclusions:
- The MONAI Label framework with AL enables effective interactive segmentation.
- Reasonable performance was achieved by a non-expert in under a month.
- This approach highlights the potential for efficient AI-driven segmentation with minimal clinical expertise.

