In Vivo Skin 3-D Surface Reconstruction and Wrinkle Depth Estimation Using Handheld High Resolution Tactile Sensing

Area of Science:

• Biomedical Engineering
• Dermatology
• Optical Imaging

Background:

• Objective dermatological assessment requires high-resolution 3-D skin surface reconstruction.
• Existing devices lack portability, validation across body sites, and consistent force sensing.

Purpose of the Study:

• To develop and validate a portable, high-resolution 3-D skin reconstruction probe.
• To enable accurate, micron-level wrinkle height estimation for dermatological applications.

Main Methods:

• A compact GelSight tactile imaging probe with a custom elastic gel and learning-based algorithm was developed.
• Integrated load cell ensured consistent contact force during measurements.
• Wrinkle depth was measured on test objects and in human participants across multiple body regions.

Main Results:

• The probe achieved a mean absolute error of 12.55 $\mu m$ on wrinkle-like test objects.
• Validated wrinkle depth metrics were obtained across multiple body regions in 15 participants.
• Statistically significant reductions in wrinkle height were observed after moisturizer application.

Conclusions:

• The developed probe is a validated tool for quantitative skin analysis.
• It offers potential for diagnosis, treatment monitoring, and skincare efficacy evaluation.
• This technology advances portable, high-resolution dermatological assessment.