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Visible-Light-Induced Direct Methylation of Quinoxalin-2(1H)-ones with N,N,N',N″,N″-Pentamethyldiethylenetriamine as
Qi Chen1, Jing Sun1, Yang Chen1
1College of Chemical Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Abstract:
Herein, a facile visible-light-driven methylation of quinoxalin-2(1H)-ones with N,N,N',N″,N″-pentamethyldiethylenetriamine as a methyl source was reported. This protocol features broad compatibility and scalability. The transformation was driven by direct irradiation with visible light, requiring no external photocatalyst. Mechanistic investigations reveal an oxygen-triggered radical pathway, excluding EDA complex or PET processes. A practical route to 3-methylquinoxalin-2(1H)-ones was thus established.
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