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Updated: Jul 19, 2026
Wide-field Fluorescent Microscopy and Fluorescent Imaging Flow Cytometry on a Cell-phone
Published on: April 11, 2013
A smartphone-combined fluorescence sensor based on porous organic polymers for determination of nitrofurans in
Dianwei Zhang1, Kexin Li1, Li Feng1
1Key Laboratory of Digital-Intelligence and Dynamic Perception for Food Quality of China Light Industry, Beijing Technology and Business University, Beijing 100048, PR China.
Abstract:
In this study, a porous organic polymer (POP)-based fluorescent sensor (Tta-DHBTA) was synthesized from 4,4',4″-(1,3,5-triazine-2,4,6-triyl)triphenylamine (Tta) and 3,3'-dihydroxy-[1,1'-biphenyl]-4,4'-dialdehyde (DHBTA) for the detection of nitrofurans (NFs). The sensor operated via static quenching, exhibiting a fluorescence emission peak at 575 nm under 465 nm excitation, which decreased proportionally with increasing NF concentrations (0.5-50 mg/L), with a detection limit (LOD) of 0.302-0.524 mg/L. For real-time monitoring, the sensor was integrated with a smartphone application. Portability and field applicability were further enhanced using a DarkBoxUVAnalyzer to convert fluorescence changes into quantifiable signals, achieving LODs of 0.278-1.494 mg/L. Spiked recovery experiments in actual samples confirmed the reliability of both the Tta-DHBTA fluorescence method and the smartphone-assisted approach. This platform provides a promising strategy for rapid, on-site environmental monitoring and food safety screening.
