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Aminopeptidase H11: from molecular characterization to vaccine development
1National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei Province 430070, PR China.
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Aminopeptidase H11 confers strong protection against Haemonchus contortus infection in its native form but lower efficacy in recombinant versions. Advances in its glycobiology, novel expression systems, and adjuvants offer solutions to overcome this hurdle. This forum aims to guide future efforts toward developing effective H11-based vaccines as sustainable alternatives to chemical control of haemonchosis.
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