Related Experiment Video
Updated: Jan 7, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
A Possible Clinical Scenario of Iodine-Containing Supplement Causing Thyroid Dysfunction in Pregnancy
Alamin Alkundi1, Jane Ohize2, Rabiu Momoh3
1Diabetes and Endocrinology, East Kent Hospitals University NHS Foundation Trust, Ashford, GBR.
None:
This report presents the case of a 33-year-old female patient with a history of Graves' disease who began using a dietary supplement (containing 150 µg of iodine and other micronutrients) to support conception. There was a laboratory finding of suppressed thyroid-stimulating hormone, high free triiodothyronine, and normal free thyroxine (suggesting thyrotoxicosis) uncovered during an early pregnancy assessment. Her thyroid levels returned to normal after she discontinued the supplement without the need for medical treatment. This case stimulated further review of the literature for the potential risks associated with improper use of iodine-containing supplements without consideration for underlying thyroid conditions and for other possible reasons for this finding.
Related Concept Videos
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Radiological Investigation I: X-ray and CT
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Vitamins
Redox Titration: Iodimetry and Iodometry
Teratogenicity

