Review of cadaver preservative solution from biomedical aspect

Area of Science:

• Anatomical Sciences
• Medical Education
• Toxicology

Background:

• Cadaveric dissection is crucial for anatomy education, necessitating effective preservation techniques.
• Traditional formaldehyde solutions pose carcinogenic and irritant risks to users and cadavers.
• Reusing cadavers requires robust preservation to maintain tissue integrity over time.

Purpose of the Study:

• To review existing research on low-formaldehyde embalming solutions for cadaver preservation.
• To evaluate the efficacy, safety, and practical application of these alternative methods.
• To inform anatomical institutes about safer preservation options.

Main Methods:

• Systematic literature search across major scientific databases (PubMed, Cochrane Library, Wiley, Google Scholar, ScienceDirect).
• Focused review on studies investigating low-formaldehyde formulations for cadaver preservation.
• Analysis of preservation effectiveness, user safety, and practical implementation.

Main Results:

• Several low-formaldehyde embalming solutions demonstrate effective cadaver preservation.
• These alternatives significantly reduce health risks compared to traditional formaldehyde.
• Various chemical compositions and application methods are available.

Conclusions:

• Low-formaldehyde embalming is essential for enhancing safety in anatomical preservation.
• Adoption of these solutions can improve user safety and cadaver integrity.
• Further research is needed to optimize solutions for diverse institutional needs, considering cost and resource availability.