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Antibiotic Resistance in Dentistry: A Review
Mohammed Zahedul Islam Nizami1,2, Iris Xiaoxue Yin2, John Yun Niu2
1Department of Mineralized Tissue Biology, ADA Forsyth Institute, 100 Chestnut Street, Somerville, MA 02143, USA.
Antibiotic resistance in dentistry is rising due to overuse, threatening oral health. Responsible prescribing and new therapies are crucial to preserve antibiotic effectiveness and ensure patient care.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Antibiotic overuse in dentistry significantly contributes to the global rise in antibiotic resistance.
- This resistance poses serious risks to both oral and overall patient health.
- Odontogenic infections necessitate antibiotics, but inappropriate prescribing is common.
Purpose of the Study:
- Review current antibiotic use in dental practices.
- Elucidate mechanisms of antibiotic resistance development.
- Identify contributing factors and propose mitigation strategies for antibiotic resistance.
Main Methods:
- This study is a narrative review of current antibiotic prescribing patterns in dentistry.
- It evaluates evidence on the unnecessary or inappropriate use of antibiotics.
- The review examines the effectiveness of conventional treatments against resistant oral pathogens.
Main Results:
- Key oral pathogens like *Streptococcus* spp., *Enterococcus faecalis*, and *Porphyromonas gingivalis* show increasing resistance.
- Contributing factors include poor guideline adherence, patient pressure, and lack of antibiotic stewardship awareness.
- Evidence-based prescribing, stewardship programs, and alternative therapies are vital.
Conclusions:
- Combating dental antibiotic resistance requires collaboration among clinicians, researchers, educators, and policymakers.
- Enhanced surveillance, stewardship policies, and innovative research are essential.
- The dental profession must commit to responsible prescribing for effective patient care.
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