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Dual-Attention EfficientNet Hybrid U-Net for Segmentation of Rheumatoid Arthritis Hand X-Rays
Madallah Alruwaili1, Mahmood A Mahmood2, Murtada K Elbashir2
1Department of Computer Engineering and Networks, College of Computer and Information Sciences, Jouf University, Sakaka 72388, Aljouf, Saudi Arabia.
Diagnostics (Basel, Switzerland)
|December 30, 2025
Summary
This study introduces a Hybrid Attention U-Net for improved radiographic image segmentation, achieving high accuracy in hand X-ray analysis. The model enhances boundary recovery and is computationally efficient for clinical applications.
Area of Science:
- Medical Imaging
- Computer Vision
- Artificial Intelligence
Background:
- Radiographic imaging segmentation is challenging due to contrast variations, artifacts, and fine anatomical details.
- Existing methods struggle with accurate boundary delineation in medical scans.
Purpose of the Study:
- To develop and evaluate a Hybrid Attention U-Net for enhanced segmentation of radiographic images.
- To improve the recovery of sharp boundaries in medical imaging analysis.
Main Methods:
- Utilized an EfficientNet-B3 encoder paired with a lightweight decoder incorporating CBAM and SCSE attention modules.
- Employed preprocessing techniques including percentile windowing, N4 bias compensation, normalization, and geometric standardization.
- Incorporated sparse geometric augmentations to mitigate domain shift.
Main Results:
- Achieved high performance in hand X-ray segmentation with Dice coefficient of 0.8426 and IoU of 0.78.
- Demonstrated rapid convergence and stable performance during training.
- Ablation studies confirmed EfficientNet-B3's contribution and the benefits of smaller batch sizes (bs=16) for regularization.
Conclusions:
- The Hybrid Attention U-Net offers a computationally moderate, end-to-end trainable solution for radiographic segmentation.
- The model shows potential for extension to multi-class problems and clinical translation.
- It provides a powerful and deployable option for musculoskeletal radiograph segmentation.

