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Updated: Jan 7, 2026

Author Spotlight: Hypothalamic Neural Mechanism Insights
Published on: August 4, 2023
Development of the neurohypophysis: A major neuroendocrine interface
Athul R Ramesh1, Naveen Nedunchezhian1, Md Hasan Ali1
1Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.
None:
The neurohypophysis is a major central neuroendocrine interface regulating reproductive functions and water homeostasis. Distinct neurovascular cell types interact via evolutionarily conserved signaling molecules in the developing neurohypophysis, providing a model system for studying principles in neuroendocrine interface morphogenesis. This review provides an overview of neurohypophysis development with a focus on paracrine signaling and the intrinsic mechanisms that regulate the major cell types and neurovascular interface development.
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