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Updated: Jan 7, 2026

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Electromagnetic Navigation Transthoracic Nodule Localization for Minimally Invasive Thoracic Surgery
Published on: May 4, 2022
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Portable Cone-Beam Computed Tomography System for Intraoperative Localization of Pulmonary Nodules: An Initial
Masahiro Mitsuoka1, Nagiko Mitsuoka1, Yuichiro Ueta1
1Department of Surgery, Kurume University School of Medicine, Fukuoka, 830-0011, Japan.
Interdisciplinary Cardiovascular and Thoracic Surgery
|December 30, 2025
Summary
Portable cone-beam computed tomography (CBCT) accurately locates small pulmonary nodules during surgery. This imaging advancement offers a flexible, real-time alternative to hybrid operating rooms for lung nodule localization.
Area of Science:
- Medical Imaging
- Thoracic Surgery
- Pulmonology
Background:
- Advancements in medical imaging enhance diagnostic and therapeutic capabilities for pulmonary nodules.
- Cone-beam computed tomography (CBCT) presents a potential alternative to hybrid operating rooms for identifying impalpable nodules.
Purpose of the Study:
- To report the initial clinical application of a portable CBCT system for intraoperative localization of small pulmonary nodules.
- To evaluate the feasibility and effectiveness of portable CBCT in a surgical setting.
Main Methods:
- Four patients with peripheral pulmonary nodules underwent localization using a portable CBCT system (Cios Spin, Siemens).
- Procedures involved general anesthesia, preoperative imaging, and intraoperative scanning with the portable CBCT system.
- Surgical clips were placed on the visceral pleura based on preoperative CT predictions.
Main Results:
- All pulmonary nodules, including ground-glass, part-solid, and small nodules, were clearly visualized with CBCT.
- Image quality was comparable to preoperative CT scans.
- The portable system demonstrated flexibility in accommodating patient positioning, with acceptable radiation exposure and no complications.
Conclusions:
- Portable CBCT enables accurate, flexible, and real-time intraoperative localization of pulmonary nodules.
- This technology can be utilized without the need for a hybrid operating room.
- This represents the first report demonstrating the clinical utility of portable CBCT for this application.
Keywords:
cone-beam computed tomography (CBCT)early-stage lung cancerground-glass nodulesmetastatic pulmonary tumourportable imagingwedge resection
