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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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Thalidomide Synergistically Regulates Cell Cycle and Endoplasmic Reticulum Stress to Alleviate RPE Oxidative Damage

Jingya Zhu1, Xinyue Yu1, Chaojuan Wen1,2

  • 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, Guangdong, China.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|December 30, 2025
PubMed

Keywords:
age‐related macular degeneration (AMD)cell cycleendoplasmic reticulum stressoxidative stressthalidomide

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