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Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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Research Progress on Personalized Bone Implants Based on Additive Manufacturing.

Bingwei Gao¹, Zhonghui Sun¹, Yanquan Tong¹

¹School of Mechanical and Power Engineering, Harbin University of Science and Technology, Harbin 150080, China.

|December 31, 2025

Summary

Personalized bone implants made with additive manufacturing offer significant orthopedic restoration advantages. Advanced materials and AI-driven design enhance complex bone repair and predict long-term implant performance.

Keywords:

CT imaging additive manufacturing artificial intelligence bone implants material properties

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Area of Science:

Biomaterials Science
Orthopedic Surgery
Manufacturing Engineering

Background:

Personalized bone implants using additive manufacturing are advancing orthopedic restoration.
These implants offer clinical advantages by matching patient anatomy and functional needs.

Purpose of the Study:

To systematically review research progress in personalized bone implants.
To analyze design, materials, fabrication, and performance evaluation within the implant research chain.

Main Methods:

Detailed analysis of personalized design methods and material selection criteria.
Evaluation of additive manufacturing processes for personalized implants.
Comprehensive assessment of implant performance indicators.

Main Results:

Multi-performance materials and intelligent manufacturing enhance complex bone repair.
Artificial intelligence transforms clinical data into long-term performance prediction models.
Additive manufacturing enables precise matching of implants to patient-specific needs.

Conclusions:

Personalized bone implants represent a significant development in orthopedic restoration.
Integration of advanced materials and AI is crucial for future complex bone repair solutions.