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Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

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Related Experiment Video

Updated: Jul 10, 2026

Application of Laparoscopic Ultrasonography in Primary Choledochal Suture during Combined Two-lens Surgery
04:03

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Published on: March 28, 2025

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Comparison of Three Gallbladder Drainage Methods for Acute Cholecystitis: A Systematic Review With Network

Lingbo Hu1,2, Yongfu Xu1,2, Aidong Wang1,2

  • 1Department of Hepatopancreatobiliary Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China.

ANZ Journal of Surgery
|December 31, 2025
PubMed
Summary
This summary is machine-generated.

Percutaneous gallbladder drainage (PTGBD) and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) show higher success rates than endoscopic transpapillary gallbladder drainage (ETGBD) for acute cholecystitis. EUS-GBD is preferred with advanced expertise, while PTGBD is a viable alternative.

Keywords:
acute cholecystitisendoscopic transpapillary gallbladder drainage cholecystostomyendoscopic ultrasound‐guided gallbladder drainagenetwork meta‐analysispercutaneous gallbladder drainage

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Area of Science:

  • Gastroenterology
  • Interventional Endoscopy
  • Surgical Risk Management

Background:

  • Acute cholecystitis treatment in high-surgical-risk patients lacks comprehensive comparative data for drainage methods.
  • Endoscopic transpapillary gallbladder drainage (ETGBD), percutaneous gallbladder drainage (PTGBD), and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) are potential options.

Purpose of the Study:

  • To compare the effectiveness of ETGBD, PTGBD, and EUS-GBD in treating acute cholecystitis in patients with elevated surgical risk.
  • To evaluate technical success, clinical success, and adverse event rates for these three gallbladder drainage modalities.

Main Methods:

  • A network meta-analysis of 17 trials involving 2254 patients was conducted.
  • Random-effects models were used to assess risk ratios (RR) and 95% confidence intervals (CI).
  • Treatments were ranked using P-scores to determine the optimal approach.

Main Results:

  • PTGBD and EUS-GBD had significantly higher technical success rates than ETGBD (RR 0.83-0.85).
  • Clinical success rates were also superior for PTGBD and EUS-GBD compared to ETGBD (RR 0.81-0.83).
  • No significant differences in procedure-related adverse events were observed among the three methods.

Conclusions:

  • Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) and endoscopic transpapillary gallbladder drainage (ETGBD) are recommended first-line treatments in centers with advanced endoscopic capabilities.
  • Percutaneous gallbladder drainage (PTGBD) serves as a crucial alternative when advanced endoscopic expertise is unavailable.