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Burden and Factors Associated with Depression and Anxiety Disorders in Pediatric Asthma: A Cross-Sectional Study

Sagad O O Mohamed1, Mohammed M I Ahmed1, Israa Elawad2

  • 1Department of Pediatrics and Child Health, University of Khartoum, Khartoum, Sudan.

Avicenna Journal of Medicine
|December 31, 2025
PubMed

Insights

Asthmatic children experience higher rates of depression and anxiety. Factors like obesity, poor health, and frequent ER visits predict these conditions, highlighting the need for integrated mental health care.

Area of Science:

  • Pediatric Health
  • Mental Health Research
  • Epidemiology

Background:

  • Asthma is common in children and linked to psychosocial issues.
  • Understanding mental health comorbidities in pediatric asthma is crucial.

Purpose of the Study:

  • To determine the prevalence of depression and anxiety in children with asthma.
  • To identify predictors of depression and anxiety in this population.

Main Methods:

  • Cross-sectional study using the 2023 National Survey of Children's Health.
  • Analyzed data from 133,963 U.S. children, with a focus on asthmatic children.
  • Employed multivariable logistic regression to identify significant predictors.

Main Results:

  • Asthmatic children showed significantly higher rates of depression (9.4%) and anxiety (21.2%) compared to non-asthmatic children.
  • Key predictors included male sex, obesity, low physical activity, poor general health, frequent ER visits, allergies, and autoimmune diseases.
  • These findings underscore a substantial psychosocial burden in pediatric asthma.

Conclusions:

  • Pediatric asthma is associated with increased depression and anxiety.
  • Identifying vulnerable subgroups through factors like health status and healthcare utilization is essential.
  • Integrated care models incorporating mental health support are recommended for asthmatic children.
Abstract

Keywords:
anxietyasthmachild healthdepression

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