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Updated: May 10, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
An Integrated Preimplantation Genetic Testing Approach with MALBAC-Based Whole-Genome Sequencing
Cheng Wan1, Fangfang Gao1, Sijia Lu2
1Department of Collaborative Innovation Center, Yikon Genomics Co., Ltd., Suzhou, Jiangsu, China.
None:
Preimplantation genetic testing (PGT) is crucial for selecting embryos free of genetic abnormalities. However, existing PGT approaches often necessitate separate platforms for aneuploidy (PGT-A), monogenic disorders (PGT-M), and structural rearrangements (PGT-SR). This can drive up costs and operational complexity when multiple PGT tests are required for a single embryo. Here, we present a MALBAC-based method that integrates PGT-A, PGT-M, and PGT-SR into one unified platform.
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