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Updated: Jan 7, 2026
Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors
Published on: March 29, 2019
Bladder masses simulating neoplasia in chronic granulomatous disease: Diagnostic challenges and spontaneous
Mehdi Dadpour1, Niloofar Soleimanifard2, Sobhan Alishah1
1Department of Urology, Shahid Labbafinejad Medical Center, The Center of Excellence in Urology, Urology and Nephrology Research Center, Research Institute for Urology and Nephrology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract:
Chronic granulomatous disease (CGD) rarely involves the lower urinary tract, and bladder mass-like lesions are exceptionally uncommon. We report a 23-year-old male with CGD who presented with gross hematuria and multiple large papillary bladder masses on imaging and cystoscopy. Cold-cup biopsies suggested papillary urothelial proliferation but were inconclusive due to limited sampling. Remarkably, repeat cystoscopy and MRI one month later showed complete resolution of all lesions. This case highlights the potential for CGD-related reactive or inflammatory changes to mimic neoplasia and emphasizes the importance of cautious interpretation and short-interval reassessment in such patients.
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