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Updated: Jan 7, 2026
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Precision of In Vivo Quantitative Tooth Wear Measurement Using Intra-Oral Scans
Published on: July 12, 2022
3.4K
An Assessment of Reproducibility Crisis in Published Randomised Controlled Trials in Oral Health - An Evaluative
Nishant Mehta1, Arpit Gupta1, Diptajit Das1,2
1Department of Oral Health Sciences, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Summary
Reproducibility in dental research is a concern, with nearly half of randomized controlled trials lacking sufficient detail for replication. Improving the clarity and comprehensiveness of published dental research is crucial for scientific advancement.
Area of Science:
- Oral Health Research
- Dental Clinical Trials
- Scientific Reproducibility
Background:
- Investigating reproducibility trends in published dental research offers insights into clarity, comprehensiveness, and replicability.
- Current trends in dental research reproducibility require examination to understand potential limitations.
Purpose of the Study:
- Identify reproducibility crises in oral health research using the Template for Intervention Description and Replication (TIDieR) checklist.
- Assess factors contributing to the lack of reproducibility in dental studies.
Main Methods:
- Evaluated randomized controlled trials (RCTs) from leading dental journals.
- Selected journals based on 2021 Journal Citation Report (JCR) impact factor.
- Appraised RCTs for reproducibility and associated factors using the TIDieR checklist.
Main Results:
- 68 RCTs were analyzed from 16 selected journals.
- The mean TIDieR checklist completion score was 71.85%.
- 51.5% of RCTs were reproducible; 48.5% were not. Studies with single interventions, non-significant findings, or crossover designs showed higher reproducibility.
Conclusions:
- Oral health RCTs demonstrate insufficient detailing, hindering replicability.
- A significant portion of dental research may not be fully reproducible due to inadequate reporting standards.
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