Case Report: Personalizing Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression for a Patient...

Area of Science:

• Neurology
• Psychiatry

Background:

• Treatment-resistant depression (TRD) presents challenges due to complex medical comorbidities.
• Existing guidelines for transcranial magnetic stimulation (TMS) lack specificity for managing high-risk patients.
• Clinicians face difficulties in determining TMS candidacy and risk management for medically complex individuals.

Purpose of the Study:

• To detail the safe and effective use of TMS in a medically complex patient with severe TRD.
• To highlight the role of interdisciplinary care coordination in managing such cases.
• To emphasize personalized treatment planning for neuromodulation access.

Main Methods:

• A case report of a 49-year-old male with major depressive disorder and comorbidities including chronic pain, hypocalcemia, and basal ganglia calcifications.
• Illustrates interdisciplinary care coordination for TMS administration.
• Focuses on personalized risk assessment and management strategies.

Main Results:

• Successfully administered TMS to a medically complex patient with severe TRD.
• Demonstrated the feasibility of safe and effective neuromodulation in a challenging clinical scenario.
• Showcased the benefit of a coordinated, individualized approach.

Conclusions:

• Interdisciplinary care coordination enables safe and effective TMS use in medically complex TRD patients.
• Personalized treatment planning is crucial for expanding access to neuromodulation.
• This case supports TMS as a viable option for select high-risk TRD patients.