Related Experiment Video
Updated: Jan 7, 2026
05:22
Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
1.7K
INTRAOCULAR POVIDONE-IODINE DURING PARS PLANA VITRECTOMY FOR SEVERE AND ATYPICAL ENDOPHTHALMITIS
Kavon Rahmani1, Michael Saad2, Kim Le3
1Department of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan.
Retina (Philadelphia, Pa.)
|January 2, 2026
Summary
Povidone-iodine (PI) infusion during pars plana vitrectomy (PPV) for endophthalmitis is safe and effective. This treatment led to significant visual acuity improvement and infection resolution in a high-risk patient group.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Endophthalmitis is a severe intraocular infection.
- Pars plana vitrectomy (PPV) is a key surgical treatment for endophthalmitis.
Purpose of the Study:
- To evaluate the safety and efficacy of povidone-iodine (PI) infusion during PPV for severe endophthalmitis.
Main Methods:
- Retrospective case series of 41 eyes with endophthalmitis.
- PPV performed with 0.025% PI in the infusion solution.
- Outcomes assessed: infection resolution, visual acuity, need for further surgery, and ocular toxicity.
Main Results:
- Infection resolved in 80.4% of eyes.
- Visual acuity improved in 70.7% of eyes.
- No ocular toxicity or vision loss linked to PI infusion was observed.
Conclusions:
- 0.025% PI infusion during PPV is safe for endophthalmitis treatment.
- Favorable post-surgical outcomes were achieved in a high-risk cohort.
Keywords:
PIPPVantimicrobial therapyantisepticatypical endophthalmitisendogenous endophthalmitisendophthalmitiseye infectionintraocular infusionmicrobial resistancepostoperative endophthalmitissevere endophthalmitissurgical managementvitrectomyMore Related Videos
Related Concept Videos
01:23Hand hygiene
5.4K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
5.4K
01:28Angle Closure Glaucoma: Treatment
1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K
01:25Glaucoma: Overview
1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K
01:27Open Angle Glaucoma: Treatment
920
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
920