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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Anogenital Warts Among Men With Human Immunodeficiency Viruses in Korea: A Single-Center Retrospective Study
Sun Hee Lee1, Jeong Hee Han2, Byoung Chul Lee2
1Department of Internal Medicine, Pusan National University School of Medicine and Medical Research Institute, Pusan National University Hospital, Busan, Korea. zzanmery@gmail.com.
Abstract:
This retrospective study analyzed data from 1,192 men living with HIV (MWH) between 2002 and 2023, and identified 76 anogenital wart cases (6.4%), which were predominantly anal (n=67). Among 20 individuals with anal warts who underwent biopsy, 25% had high-grade squamous intraepithelial lesions (SILs). Of 15 individuals with low-grade SILs, one progressed to high-grade SIL after 5 years, and two developed anal cancer at 5 and 15 years. High-risk human papillomavirus genotypes were detected in 42.9% of tested specimens. These findings highlight the importance of routine screening and early detection of precancerous lesions in MWH in Korea.
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