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Physical Performance, Sarcopenia and Malnutrition-Basic Test Set for Everyday Use in Cancer Therapy
S Einhell1, M Albrecht2, S Windschüttl2
1Department of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany.
Cancer Medicine
|January 5, 2026
Summary
A streamlined approach using grip strength, bioelectrical impedance analysis, and Sit-to-Stand tests can efficiently screen cancer patients for malnutrition and sarcopenia risk, reducing assessment time by 70% for clinical routine integration.
Area of Science:
- Oncology
- Geriatrics
- Clinical Nutrition
Background:
- Physical performance, malnutrition, and sarcopenia screening are recommended for hematological-oncological patients.
- Current clinical practice faces challenges in routine implementation due to economic constraints and numerous testing options.
Purpose of the Study:
- To propose a practical, time-efficient compromise for routine malnutrition and sarcopenia testing in cancer patients.
- To reduce the time and resources required for diagnostic assessments.
Main Methods:
- A prospective, monocentric cohort study involving 29 cancer patients.
- Investigated time for malnutrition screening (PG-SGA long form), diagnostics (GLIM), and sarcopenia diagnostics (EWGSOP II).
- Utilized correlation analyses to identify and reduce redundant tests.
Main Results:
- Identified high prevalence of malnutrition (55.2%) and sarcopenia risk (20.7%) in the cohort.
- Initial assessment required 19 minutes, even by the third visit.
- Correlation analysis revealed that a reduced set of 3 assisted tests took only 6 minutes.
Conclusions:
- A three-test approach (grip strength, bioelectrical impedance analysis, Sit-to-Stand) diagnosed 96.6% of patients at risk.
- Reduced assessment time by 70%, making it suitable for daily clinical routine.
- This practical compromise facilitates guideline recommendations in routine care.
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