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Updated: Jan 7, 2026

Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes
Published on: November 21, 2017
Asymmetric Ring Opening of Oxabicyclic Alkenes: Enhanced Rhodium Catalysis Using Camphor-Derived NHC Ligands
Daniel Kamzol1, Wende Chen1, René Wilhelm1
1Institute of Organic Chemistry, Clausthal University of Technology, Leibnizstrasse 6, 38678 Clausthal-Zellerfeld, Germany.
Abstract:
The synthesis, characterization, and reactivity assessment of a chiral camphor-based Rh(I) catalyst functionalized with a pyridine moiety is presented. The catalytic system was evaluated in the asymmetric ring opening (ARO) of bicyclic alkene substrates, ensuring high product yields and enantioselectivity. While the primary focus was on the use of indoles as nucleophiles in the ARO reaction, a broader scope of bicyclic substrates was also explored. The catalyst demonstrated tolerance toward various functional groups present in the nucleophiles, underscoring its broad synthetic utility in asymmetric synthesis.
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