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Updated: Jan 7, 2026

Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
Published on: January 7, 2016
KBG Syndrome: A Case Report and Longitudinal Assessment of Long-Acting Recombinant Human Growth Hormone Therapy
Hui Nan1, Pu Zhang2, Jing Qian1
1Department of Pediatrics and Child Health Liaocheng People's Hospital Liaocheng China.
Abstract:
This case analysis examines the clinical data, molecular genetic testing results, and 20-month clinical data of long-acting recombinant human growth hormone (rhGH) treatment in a child with KBG syndrome (KBGS). The child exhibited a c.1591delG frameshift mutation in the ANKRD11 gene associated with KBGS, a variant not previously reported, thereby enriching the genetic mutation spectrum of KBGS. Following treatment with long-acting rhGH, the child showed significant improvement in height without adverse reactions.
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