A phase 2 randomized controlled trial using biologics to improve multi OIT outcomes (COMBINE): design, rationale, and

A J Long1, S Sindher1, K Martinez1

  • 1Department of Pathology, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, CA, United States.

Frontiers in Allergy
|January 5, 2026
PubMed
Summary

This study investigates combining biologics like omalizumab and dupilumab with multi-food oral immunotherapy (mOIT) to improve food allergy treatment. The goal is to enhance desensitization and reduce side effects for better patient outcomes.

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