Related Experiment Video
Updated: Jan 7, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
Primary Gastrointestinal B-Cell Lymphomas: A Clinicopathological Review
Ibrahim Elsharawi1, Christopher Liwski1
1Department of Hematological Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
None:
The gastrointestinal tract is the most frequent extranodal site for lymphomas. Primary gastrointestinal B-cell lymphomas represent a distinct group of lymphoproliferative disorders and are the most common type of gastrointestinal lymphomas. Their pathogenesis, clinicopathological characteristics, and prognosis may differ from their nodal or systemic counterparts, emphasizing the importance of accurately identifying them. This review incorporates some of the latest literature on common primary gastrointestinal B-cell lymphomas focusing on their unique pathogenic mechanisms, clinical features, and pathological findings. It also addresses the prognostic outcomes associated with these lymphomas and provides a brief overview of the available treatment options.
Related Concept Videos
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Lymphoid Cells and Tissues
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
B Cell Activation and Differentiation
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
Cells of the Adaptive Immune Response

