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Updated: Jan 13, 2026

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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
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[Perinatal depression: a common condition with major implications for women's health]
1INSERM U1266, Université Paris Cité, AP-HP, Hôpital Louis Mourier, Colombes, France.
Summary
Perinatal depression affects 10-20% of women post-childbirth. Early diagnosis and integrated care are crucial for maternal mental health, child development, and family well-being.
Area of Science:
- Obstetrics and Gynecology
- Psychiatry
- Public Health
Background:
- Perinatal depression impacts 10-20% of women postpartum.
- It often goes undiagnosed, affecting maternal mental health, child development, and family dynamics.
- Understanding its scope is vital for effective intervention.
Purpose of the Study:
- To review the epidemiology and risk factors of perinatal depression.
- To describe its clinical manifestations.
- To emphasize the need for systematic screening and integrated care.
Main Methods:
- Literature review of perinatal depression.
- Analysis of epidemiological data.
- Synthesis of clinical manifestations and risk factors.
Main Results:
- Identified prevalence rates and key risk factors.
- Detailed distinct clinical presentations.
- Highlighted underdiagnosis challenges.
Conclusions:
- Systematic screening and expert assessment are essential.
- A stepped care approach integrating various interventions is recommended.
- Multidisciplinary collaboration is key for managing perinatal depression.
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