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Related Experiment Video

Updated: Jan 13, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
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A Rare Association of Reactive Retinal Astrocytic Tumor With Chronic Rhegmatogenous Retinal Detachment.

Vicente Lorenzo O Cabahug1,2, Anita Chan1,3, Andrew S H Tsai1,3

  • 1Singapore National Eye Centre, Singapore Eye Research Institute, Singapore.

Retinal Cases & Brief Reports
|January 6, 2026
PubMed
Summary

A rare reactive retinal astrocytic tumor (RRAT) was found in an elderly patient with chronic rhegmatogenous retinal detachment (RRD). Histopathology confirmed the diagnosis, guiding tailored surgical management for this unusual ocular condition.

Keywords:
)Glial tumorsReactive retinal astrocytic tumor (RRAT)Retinal surgeryRhegmatogenous retinal detachment (RRD)Vasoproliferative tumor (VPT

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Transcriptomic Analysis of Human Retinal Surgical Specimens Using jouRNAl
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Area of Science:

  • Ophthalmology
  • Surgical Pathology

Background:

  • Reactive retinal astrocytic tumors (RRATs) are rare ocular neoplasms.
  • Chronic rhegmatogenous retinal detachment (RRD) can have various etiologies.

Purpose of the Study:

  • To document a case of RRAT associated with chronic RRD.
  • To highlight the diagnostic and management challenges of this rare co-occurrence.

Main Methods:

  • A single, retrospective case report of an 82-year-old male.
  • Surgical intervention included phacoemulsification, scleral buckling, and pars plana vitrectomy.
  • Excisional biopsy and histopathological analysis were performed.

Main Results:

  • The patient presented with vision loss and chronic RRD.
  • An incidentally discovered nodular mass was biopsied and confirmed as RRAT.
  • Postoperative retinal reattachment and some visual improvement were achieved.

Conclusions:

  • This case highlights a rare association between occult RRAT and chronic RRD.
  • Accurate histopathologic examination is crucial for diagnosing RRAT.
  • Surgical strategies should consider tumor characteristics and associated retinal complications.