Allosteric activation of RNF20/RNF40-RAD6A-mediated H2BK120 monoubiquitylation by H2BS112 GlcNAcylation

Zhiheng Deng1,2,3, Shixian Tao2, Yunxiang Du2

  • 1School of Pharmaceutical Sciences, Institute of Translational Medicine, Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, Shanghai Jiao Tong University, Shanghai, China.

Nature Chemical Biology
|January 6, 2026
PubMed

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