Associations of Couples' Psychedelic Use with Shared Reality and Relational Well-Being

The resurgence in research with classic psychedelics (e.g. LSD, psilocybin) underscores their potential for improved well-being; however, the interpersonal context and mechanisms of psychedelic impacts remain unknown. In a sample of 798 participants (81 couples), this survey study tested whether use of a psychedelic with a romantic partner (v. not together) was associated with couples' shared understanding (i.e. shared reality) and changes in relational well-being. Multilevel dyadic analyses provided overwhelming support for hypotheses that taking a psychedelic together would be associated with greater shared reality and more positive relational changes (e.g. improved physical intimacy, emotional closeness, satisfaction). Shared reality mediated positive relational changes. Taking a psychedelic alone was indirectly associated with the decision to end a romantic relationship. Although limited by cross-sectional design and low dyadic participation, results emphasize the importance of a socially informed approach to the development of psychedelic therapies, with potential to increase treatment effectiveness and mitigate harms.