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Related Concept Videos

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Urinary Tract Calculi VI: Surgical Management01:25

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Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
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Kidney Transplant I: Introduction01:28

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Urinary Tract Calculi III: Medical Management01:30

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The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
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Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

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Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
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Single Port Donor Nephrectomy
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Donor-gifted nephrolithiasis: case-based analysis and comparative study.

Maxwell Sandberg1, Mark Xu1, Randall Bissette1

  • 1Department of Urology, Wake Forest Baptist Medical Center, Winston Salem, NC 27101, USA.

The Canadian Journal of Urology
|January 7, 2026
PubMed
Summary
This summary is machine-generated.

Donor-gifted nephrolithiasis, or kidney stones in deceased donor (DD) kidneys, is very rare in kidney transplants. This study found favorable patient and graft outcomes, suggesting transplantation is feasible even with known stones.

Keywords:
deceased donor kidney percutaneous nephrolithotomynephrolithiasisstonetransplant

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Area of Science:

  • Nephrology
  • Transplant Surgery
  • Urology

Background:

  • Donor-gifted nephrolithiasis is a rare complication in deceased donor (DD) kidney transplantation.
  • Limited research exists, lacking established guidelines for donor kidney stone management.
  • This variability impacts donor kidney selection and recipient care.

Purpose of the Study:

  • To determine the frequency of donor-gifted nephrolithiasis in DD kidney transplant recipients.
  • To analyze patient and graft outcomes in recipients with donor-gifted kidney stones.
  • To evaluate the safety and feasibility of transplanting kidneys with pre-existing stones.

Main Methods:

  • Retrospective review of DD renal transplants and postoperative care at Wake Forest Baptist Medical Center (1979-2025).
  • Identification of donor-gifted stones discovered during or within two weeks post-transplant.
  • Comparison of stone size between treated and surveilled patients; analysis of patient and graft outcomes.

Main Results:

  • Eight of 4723 DD renal transplants (0.2%) had donor-gifted nephrolithiasis.
  • Median stone size was 8 mm; 38% of patients received treatment, 62% underwent surveillance.
  • Graft failure occurred in 25% of recipients, with one case linked to stone treatment.

Conclusions:

  • Donor-gifted nephrolithiasis is exceptionally rare in DD kidney transplantation.
  • Favorable patient and graft outcomes support the feasibility of transplanting DD kidneys with known stones.
  • Further research may refine management strategies for this rare condition.