Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

14.8K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
14.8K
Scanning Electron Microscopy01:07

Scanning Electron Microscopy

5.3K
A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
Fundamental Principles
Accelerated...
5.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiscale Analysis of Electrochemical Dealloying of Bimetallic Nanoparticles to Tune Catalytic Activity.

ACS applied materials & interfaces·2026
Same author

Electrochemical imaging of thermochemical catalysis.

Nature catalysis·2026
Same author

Revealing grain dependent glucose oxidation pathways on gold with scanning electrochemical cell microscopy.

Chemical communications (Cambridge, England)·2026
Same author

Optimizing Electrochemical Microprinting of Conducting Polymers: Scanning Electrochemical Cell Microscopy (SECCM) Coupled with Conveyor-Belt Surface Analysis.

Small methods·2025
Same author

Optical and Electron Transparent Polycrystalline Boron Doped Diamond Membranes for Nanoscale Correlative Structure-Electrochemical Measurements.

ACS nano·2025
Same author

Surface Structure and Grain Boundary Effects on the Oxygen Evolution Reaction at Gold Electrodes.

ACS electrochemistry·2025
Same journal

Aptamer-Based Scanning Electrochemical Microscopy for Specific and Localized Detection of Analyte Concentration.

ACS electrochemistry·2026
Same journal

Mechanistic Insights into the Suppression of Proton Intercalation and the Hydrogen Evolution Reaction through Phosphorus Doping in Tungsten Oxide.

ACS electrochemistry·2026
Same journal

Size-Dependent Oxidation of Copper Nanostructured Electrocatalysts Produced by Spark Ablation.

ACS electrochemistry·2026
Same journal

Oxidative Stability and Redox Coupling in 3,4,3-LI(1,2-HOPO) <i>f</i>‑Element Complexes under Acidic Conditions.

ACS electrochemistry·2026
Same journal

Heterogeneous PFAS Defluorination and Fluoride Upcycling into Medicinal Agents in Aqueous Electrolytes.

ACS electrochemistry·2026
Same journal

Optimization of Subsecond Estradiol Detection through Analysis of Surface-Analyte Interactions.

ACS electrochemistry·2026
See all related articles

Related Experiment Video

Updated: Jan 13, 2026

Scanning-probe Single-electron Capacitance Spectroscopy
10:53

Scanning-probe Single-electron Capacitance Spectroscopy

Published on: July 30, 2013

13.4K

A Look inside a Flexible Open-Source Scanning Electrochemical Probe Microscope.

Kim McKelvey1, Martin Andrew Edwards2, Minkyung Kang3,4

  • 1MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University of Wellington, Wellington 6012, New Zealand.

ACS Electrochemistry
|January 7, 2026
PubMed
Summary
This summary is machine-generated.

This study presents a flexible, open-source scanning electrochemical probe microscopy (SEPM) instrument. This adaptable SEPM system enables various surface and interface analyses with minimal user programming, benefiting both new and expert researchers.

Keywords:
Scanning electrochemical cell microscopyelectrochemical imaginginstrumentationnanoelectrochemistryscanning electrochemical microscopyscanning ion conductance microscopy

More Related Videos

Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope AFM-SECM
08:31

Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope AFM-SECM

Published on: February 10, 2021

7.4K
Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys
12:18

Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys

Published on: June 27, 2022

3.3K

Related Experiment Videos

Last Updated: Jan 13, 2026

Scanning-probe Single-electron Capacitance Spectroscopy
10:53

Scanning-probe Single-electron Capacitance Spectroscopy

Published on: July 30, 2013

13.4K
Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope AFM-SECM
08:31

Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope AFM-SECM

Published on: February 10, 2021

7.4K
Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys
12:18

Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys

Published on: June 27, 2022

3.3K

Area of Science:

  • Electrochemistry
  • Surface Science
  • Microscopy

Background:

  • Scanning electrochemical probe microscopy (SEPM) utilizes electrochemical probes to analyze surface and interface properties.
  • Existing SEPM instruments vary in probe type and measurable physicochemical properties (e.g., charge transfer, topography).
  • A flexible instrument can provide access to a wide range of SEPM techniques like SECM, SICM, and SECCM.

Purpose of the Study:

  • To detail a flexible, open-source SEPM instrument.
  • To demonstrate its capability for common and user-defined SEPM methodologies with minimal programming.
  • To highlight the advantages of FPGA architecture in electrochemical instrumentation.

Main Methods:

  • Development of a flexible open-source SEPM instrument.
  • Utilization of a field programmable gate array (FPGA)-based data acquisition card.
  • Implementation of common SEPM operation modes and hyphenated techniques using software and hardware descriptions.

Main Results:

  • The described instrument facilitates common and widely applicable SEPM techniques and experimenter-defined methodologies.
  • FPGA architecture is shown to be beneficial for electrochemical instrumentation.
  • Examples illustrate the implementation of SEPM modes and custom scanning protocols.

Conclusions:

  • The open-source SEPM instrument offers widespread access to SEPM techniques.
  • The instrument design and FPGA architecture simplify complex SEPM experiments.
  • This work serves as a tutorial for both expert and novice SEPM users, encouraging instrument development and optimization.