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Updated: Jan 13, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
A Rare Case of Necrotising Sarcoid Granulomatosis Presenting as Bilateral Pulmonary Masses Mimicking Malignancy
Jacqueline Chung1, Rory O'Donnell1, Ayan Sabih1
1Waikato Hospital Hamilton New Zealand.
Abstract:
Necrotising sarcoid granulomatosis (NSG) is a rare granulomatous lung disease characterised by non-caseating granulomas, necrosis, and vasculitis. We describe a 50-year-old man who presented with constitutional symptoms and bilateral pulmonary masses initially suggestive of metastatic malignancy. Extensive infectious, malignant, and autoimmune workup was negative. Histopathology from lung biopsies and a video-assisted thoracoscopic surgery (VATS) resection revealed granulomatous inflammation with necrosis and no evidence of malignancy or infection. A trial of corticosteroids resulted in clinical, biochemical, and radiological improvement. This case highlights the diagnostic challenges of NSG and the importance of multidisciplinary evaluation to avoid misdiagnosis.
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