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An invasive Aspergillus flavus infection in an extremely preterm neonate: a case report
Neema Pithia1, Margie Morgan2, Thea Tagliaferro3
1Division of Pediatric Infectious Diseases, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Abstract:
Extremely preterm neonates are at heightened risk for invasive fungal infections. We report a fatal case of Aspergillus flavus infection in a 25-week infant, outlining the clinical course, antifungal treatment, and challenges in management. This case highlights the need for early recognition, rapid biopsy and aggressive therapy in vulnerable neonates.
Insights
Invasive fungal infections pose a significant risk to extremely preterm neonates. This case details a fatal Aspergillus flavus infection, emphasizing early diagnosis and aggressive treatment for vulnerable infants.
Area of Science:
- Neonatology
- Infectious Diseases
- Mycology
Background:
- Extremely preterm neonates (<25 weeks gestation) are highly susceptible to invasive fungal infections.
- Invasive fungal infections in neonates can lead to severe morbidity and mortality.
- Aspergillus species are an emerging cause of invasive fungal infections in critically ill neonates.
