Macro-Aspartate Aminotransferase With Metabolic Dysfunction-Associated Fatty Liver Disease in Adults:Report of One...

Macro-aspartate aminotransferase(AST)is a macro-enzyme formed by self-polymerization or binding to other serum components that are difficult to be cleared by the kidneys,resulting in an isolated elevation in serum AST.Macro-AST is a rare disease.In this report,a case with isolated AST elevation as the main manifestation is presented.The diagnosis of macro-AST was established by the polyethylene glycol precipitation assay.The comprehensive history and exclusion of other factors suggest that this case of macro-AST may be secondary to metabolic dysfunction-associated fatty liver disease.