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Related Concept Videos

Ethics in Research01:56

Ethics in Research

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Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
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Updated: Jan 13, 2026

Transition of Farm Pigs to Research Pigs using a Designated Checklist followed by Initiation of Clicker Training - a Refinement Initiative
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Building a humane scientific future: Second Asia Laboratory Animal Day.

Vijay Pal Singh1, Himalaya Bhardwaj2, R K Shakthi Devan1

  • 1Laboratory Animal Scientist's Association (LASA), Delhi, India.

Animal Models and Experimental Medicine
|January 8, 2026
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Summary
This summary is machine-generated.

This study outlines best practices for laboratory animal handling and experimental design, emphasizing ethical oversight and the 3Rs (Replacement, Reduction, Refinement) to ensure good science with good care.

Keywords:
3RAFLASLASA India

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Area of Science:

  • Laboratory animal science
  • Research methodology
  • Animal welfare

Background:

  • Ethical frameworks like CCSEA & IAEC oversight are crucial.
  • The 3Rs (Replacement, Reduction, Refinement) guide responsible research.
  • Transparent documentation is essential for ethical compliance.

Purpose of the Study:

  • To detail best practices in laboratory animal handling and experimental design.
  • To bridge the gap between ethical considerations and scientific excellence.
  • To promote a culture of responsible research.

Main Methods:

  • Covers handling and anatomy of mice, rats, rabbits, and guinea pigs.
  • Details administration routes (SC, IM, IP, IV) and blood sampling techniques.
  • Includes husbandry, nutrition, health monitoring, and experimental design principles like randomization and blinding.

Main Results:

  • Hands-on training covers handling, restraint, injections, and cage management.
  • Emphasis on endpoint assessment and humane techniques.
  • Outcomes include enhanced animal welfare and improved data reliability.

Conclusions:

  • Integrating ethics with expertise and experimental rigor leads to responsible research excellence.
  • Skilled personnel are vital for ethical compliance and data integrity.
  • Adherence to these principles enhances animal welfare and research outcomes.