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AI for Detecting and Predicting Postpartum Depression: Scoping Review
Mais Alkhateeb1,2,3, Ajisha Nayeem2, Arfan Ahmed2
1College of Education and Art, Lusail University, Doha, Qatar, +974440119502.
Journal of Medical Internet Research
|January 8, 2026
Summary
Artificial intelligence (AI) shows promise in identifying mothers at risk for postpartum depression (PPD). However, current research on AI for PPD detection and prediction needs more robust validation and diverse data.
Area of Science:
- Medical Informatics
- Computational Psychiatry
- Machine Learning in Healthcare
Background:
- Postpartum depression (PPD) affects a significant portion of mothers globally, necessitating improved early detection methods.
- Existing screening tools for PPD often lack scalability and predictive accuracy.
- Artificial intelligence (AI), encompassing machine learning, deep learning, and natural language processing, offers enhanced capabilities for accurately identifying mothers at risk of PPD.
Purpose of the Study:
- To systematically map and analyze the existing literature on artificial intelligence (AI)-based methods for detecting and predicting postpartum depression (PPD).
Main Methods:
- A comprehensive scoping review was conducted following PRISMA-ScR guidelines.
- Empirical studies utilizing AI for PPD detection or prediction were systematically searched across eight major databases.
- Data extraction focused on study characteristics, AI models, data sources, preprocessing, validation, and performance metrics, followed by narrative synthesis.
Main Results:
- 65 studies met inclusion criteria, with the majority from the United States and published in 2024.
- AI models were predominantly used for PPD prediction (80%) over detection (22%), with sociodemographic, psychological, and obstetric data being primary inputs.
- Machine learning, particularly ensemble-based boosting models, showed superior performance, though studies often lacked external validation and standardized reporting.
Conclusions:
- The review highlights the dominance of classical machine learning in AI-driven PPD research.
- There is limited adoption of deep learning and advanced preprocessing techniques, alongside inconsistent validation strategies.
- Future research should address limitations such as small sample sizes, geographic bias, and the need for standardized, multimodal data approaches for more reliable PPD prediction.

