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Respiratory syncytial virus (RSV) vaccine choices during pregnancy

Bing Wang1, Prabha Andraweera1, Gang Chen2

  • 1Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, Adelaide, South Australia, Australia; Robinson Research Institute and Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.

Public Health
|January 8, 2026
PubMed

Insights

Australian pregnant women prefer free maternal Respiratory Syncytial Virus (RSV) vaccines, prioritizing safety and effectiveness. Preferences for promotion strategies varied among vaccine accepters and rejecters.

Area of Science:

  • Public Health
  • Vaccinology
  • Maternal and Child Health

Background:

  • Respiratory Syncytial Virus (RSV) is a major cause of infant respiratory illness.
  • New maternal RSV vaccines and infant monoclonal antibodies offer protection.
  • Understanding vaccine attitudes in pregnant populations is crucial for public health strategies.

Purpose of the Study:

  • To assess Australian pregnant women's attitudes towards maternal RSV vaccination.
  • To identify factors influencing decisions regarding RSV vaccination in pregnancy.
  • To compare preferences between maternal vaccination and infant monoclonal antibody administration.

Main Methods:

  • A cross-sectional online survey with a discrete choice experiment (DCE) design was used.
  • Focus group discussions informed the DCE survey development.
  • Mixed logit and latent class models analyzed survey data from 440 participants.

Main Results:

  • Pregnant women strongly preferred a free maternal RSV vaccine with high effectiveness and low side effect risk.
  • Two preference groups emerged: 'accepters/deliberators' (68.3%) and 'rejecters' (31.7%).
  • Maternal RSV vaccination was significantly preferred over infant monoclonal antibodies (54.8% vs. 16.8%).

Conclusions:

  • Maternal RSV vaccination is generally well-received by pregnant women when offered at no cost.
  • Preference for promotional strategies differed between vaccine accepters and rejecters.
  • Targeted communication strategies may be necessary to address varied attitudes towards RSV vaccination.
Abstract

Keywords:
AttitudesPregnancyRSVVaccine

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