Simultaneous Therapy Approach: Systemic and Intratympanic Corticosteroid for Idiopathic Sudden Sensorineural Hearing...

Area of Science:

• Otolaryngology
• Neurology
• Pharmacology

Background:

• Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL) presents a significant clinical challenge.
• Various treatment modalities exist for ISSNHL, with corticosteroids being a primary therapeutic option.

Purpose of the Study:

• To evaluate the efficacy of combined systemic and intratympanic corticosteroid injections for ISSNHL.
• To assess the impact of this combined therapy on hearing recovery and associated symptoms.

Main Methods:

• A cohort of 73 patients diagnosed with ISSNHL was studied.
• Patients received a treatment regimen combining systemic and intratympanic corticosteroid injections.
• Hearing outcomes and symptom relief were assessed using Modified Siegel's criteria one month post-treatment.

Main Results:

• Approximately 60% of patients experienced some degree of hearing improvement (30% complete, 14% partial, 16% slight).
• Significant symptom relief was observed: 24% complete and 51% partial relief for tinnitus; 67% complete and 33% partial relief for vertigo.

Conclusions:

• Combined systemic and intratympanic corticosteroid treatment demonstrates considerable effectiveness in managing ISSNHL.
• This therapeutic approach successfully addresses both hearing deficits and debilitating symptoms such as tinnitus and vertigo in ISSNHL patients.