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Updated: May 12, 2026

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Pembrolizumab-Induced Tubulointerstitial Nephritis in Early-Stage Triple-Negative Breast Cancer: A Case Report

Catarina Ferreira1, Cristiana H Martins1, Renata Carvalho2

  • 1Medical Oncology, Braga Local Health Unit, Braga, PRT.

Cureus
|January 9, 2026
PubMed
Summary

Immune checkpoint inhibitors (ICIs) like pembrolizumab can cause acute kidney injury (AKI). Early recognition and corticosteroid treatment of this pembrolizumab-induced AKI are crucial for kidney recovery.

Keywords:
acute tubulointerstitial nephritisearly-stage triple-negative breast cancerimmune checkpoint inhibitorsimmune-related adverse eventspembrolizumab

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