Related Experiment Video

Updated: Jan 13, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

15.0K

LINKS BETWEEN DYSLIPIDEMIA AND RISK FACTORS IN ACUTE CORONARY SYNDROME

M Osman1, A Alawad2, T Merghani3

  • 11Sudan Medical Specialization Board, Khartoum, Sudan.

Georgian Medical News
|January 9, 2026
PubMed

Insights

Dyslipidemia is linked to acute coronary syndrome (ACS). High triglycerides correlate with poor glycemic control in ACS patients, highlighting the need for triglyceride management, especially in diabetics.

Area of Science:

  • Cardiology
  • Metabolic Disorders
  • Clinical Research

Background:

  • Dyslipidemia, a lipid profile abnormality, is a significant contributor to acute coronary syndrome (ACS).
  • Understanding the interplay between lipid abnormalities and traditional cardiovascular risk factors is crucial for effective prevention and management strategies.
  • This study investigates lipid profile abnormalities in ACS patients and their associations with demographic, clinical, and metabolic variables.

Purpose of the Study:

  • To estimate the prevalence of lipid profile abnormalities in patients diagnosed with ACS.
  • To examine the relationship between lipid abnormalities and demographic, clinical (smoking, hypertension, diabetes mellitus), and metabolic risk factors in ACS patients.

Main Methods:

  • A cross-sectional study involving 231 ACS patients was conducted at Madani Heart Center, Sudan.
  • Data collected included demographic characteristics, cardiovascular risk factors, and biochemical markers (LDL, HDL, TG, HbA1c, random blood glucose).
  • Statistical analyses included descriptive statistics, ANOVA, Chi-square tests, and bivariate correlations (p≤0.05).

Main Results:

  • Elevated triglycerides (TG) showed a positive correlation with glycated hemoglobin (HbA1c) and random blood glucose, indicating a link between dyslipidemia and glycemic control.
  • High-density lipoprotein (HDL) cholesterol correlated positively with body weight.
  • Low-density lipoprotein (LDL) cholesterol and TG levels did not show significant associations with ACS types, smoking, or hypertension.

Conclusions:

  • Triglyceride levels are significantly associated with impaired glycemic control markers in ACS patients.
  • These findings underscore the importance of managing triglyceride levels, particularly in diabetic individuals with ACS.
  • Further research into lipid management strategies for ACS patients with dyslipidemia and diabetes is warranted.
Abstract

More Related Videos

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

9.7K
Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation06:47

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation

Published on: January 28, 2021

12.3K

Related Concept Videos

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
347
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
869
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
207
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
890
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
360
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
262