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Updated: Jan 13, 2026

Estimation of Telomeric Repeat-containing RNA from DNA/RNA Hybrid Complexes
Published on: December 5, 2025
A trunkload of ancient RNA
Sébastien Calvignac-Spencer1, Carles Lalueza-Fox2
1Helmholtz Institute for One Health, Helmholtz Centre for Infection Research, Greifswald, Germany; Faculty of Mathematics and Natural Sciences, University of Greifswald, Greifswald, Germany.
Abstract:
Ancient DNA has become a workhorse for evolutionary biologists. In contrast, ancient RNA studies have been rare and often methodologically controversial. Mármol-Sánchez et al. provide compelling evidence that aRNA survived up to ca. 50,000 years in permafrost-preserved mammoth (Mammuthus primigenius) soft tissues. Will this finally pave the way for paleotranscriptomics?
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