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Phytochemicals: Principles and Practice
1Department of Health, Cognition, and Behavior, University College Roosevelt, 4330 AB Middelburg, The Netherlands.
Phytochemicals, plant compounds with ecological roles, show significant therapeutic potential for chronic diseases. This review explores their diverse applications and challenges for healthcare integration.
Area of Science:
- Plant biochemistry and medicinal chemistry.
- Focuses on plant-derived secondary metabolites and their pharmacological applications.
Background:
- Phytochemicals are plant compounds crucial for ecological defense.
- They possess pharmacological properties beneficial for human health, targeting chronic diseases.
- Includes flavonoids, polyphenols, alkaloids, and terpenoids.
Purpose of the Study:
- To comprehensively review phytochemical roles in plant physiology and human therapeutics.
- Examine structural diversity, biosynthesis, ecological significance, and biomedical applications.
- Address challenges in extraction, bioavailability, delivery systems, and healthcare integration.
Main Methods:
- Literature review synthesizing current research on phytochemicals.
- Analysis of structural diversity, biosynthetic pathways, and ecological functions.
- Exploration of extraction techniques, bioavailability, and nanoencapsulation delivery systems.
Main Results:
- Phytochemicals exhibit broad pharmacological efficacy against cancer, cardiovascular, and neurodegenerative disorders.
- Advanced extraction and delivery systems like nanoencapsulation improve bioavailability and clinical translation.
- Policy and perception barriers hinder mainstream healthcare integration.
Conclusions:
- Phytochemicals offer sustainable and accessible solutions for global health disparities.
- Further research and policy changes are needed to fully integrate these compounds into healthcare.
- Highlighting the potential of phytochemicals for preventative and therapeutic applications.
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